Have you heard...?
ToxRat sets the course for the future!
actually, we hoped to meet users, business partners and colleagues - that is YOU - at the upcoming annual SETAC meeting in May.
However – this will not work due to the ongoing pandemic. This means: one more year without personal contact, face-to-face discussions and informal information about ToxRat´s future.
That is a great pitty – since indeed, we have a lot of plans and ideas. For some time now we have been dealing with the question: How to set the course for ToxRat´s future? Let me briefly tell you the most important aspects:
News on NOEC determination
A recently published paper confirms the relevance of CPCAT for the analysis of count data:
Daniels, B., Roß‐Nickoll, M., Jänsch, S., Pieper, S., Römbke, J., Scholz‐Starke, B. and Ottermanns, R. (2021), Application of the Closure Principle Computational Approach Test to Assess Ecotoxicological Field Studies: Comparative Analysis Using Earthworm Field Test Abundance Data. Environ Toxicol Chem
The CPCAT will be implemented in the next ToxRat update.
Further information can be also found here:
Lehmann et al. 2018: https://doi.org/10.1186/s12302-018-0178-5
Lehmann et al. 2016: https://link.springer.com/article/10.1007/s00477-015-1079-4
Seminars and Trainings 2.0
We changed our seminars and trainings to online format. Initial experiences with online training were very positive, so we are now expanding and continuing this format. Please contact us if you are interested!
ToxRat, Corona and the SETAC Europe Annual Meeting, Dublin
Due to measures against the coronavirus, the SETAC Europe 30th Annual Meeting on 3-7 May will be held in the virtual space.
We fully agree with this decision and greatly appreciate the immense efforts of the organizers, to bear this extraordinary challenge on such short notice.
Please read our message to visitors of the virtual exhibition here.
We wish SETAC and all participants great success at the virtual meeting!
Hope to see you again soon. Take care!
Guideline developement for Glyceria maxima and ringtesting is still going on. A poster presented at the SETAC North America Meeting, Totonto, shows the current state and answers the question, whether root variables are appropriate endpoints.
From 2019 to 2022, ToxRat will again participate in a project of the German Federal Environment Agency (Umweltbundesamt) investigating the toxicity and environmental compatibility of construction products for outdoor applications.
Further information is available here (in German):
ToxRat again is an exhibitor at the SETAC-Europe-Annual Meeting, to be held from May 26-30 in Helsinki, Finnland. We are looking forward to meet you (again) at booth no 22.
New training course: Statistical Power Analysis
Since January, we are offering additional training courses about statistical power analysis and experimental designs of ecotoxicological semi-field and field studies.
The course introduces theoretical principles of hypothesis testing, a-priori considerations for sound experimental designs and measures of after-the-fact reliability of study results. Beyond theory, the focus lies on practical exercises using open-source software tools and gives room for discussion of the specific problems of the participants. For this reason, using your own data is highly welcome. As usual, the specific contents might be customized. Just let us know your needs!
To be continued: News regarding NOEC-determination from reproduction data
René Lehmann, Jean Bachmann, Bilgin Karaoglan, Jens Lacker, Glenn Lurman, Christian Polleichtner, Hans Toni Ratte and Monika Ratte (2018):
The CPCAT as a novel tool to overcome the shortcomings of NOEC/LOEC statistics
in ecotoxicology: a simulation study to evaluate the statistical power.
Environ Sci Eur (2018) 30:50
Update ToxRat 3.3.0 released.
Details about "What is new in ToxRat 3.3.0" are to be found in the customer area.
ToxRat Solutions again attended the SETAC Europe Meeting 2018 from 13th to 17 th May as exhibitor . We enjoyed both a lot of new contacts and meeting again several existing users. Thanks to all who joined us!
We also contributed to a poster presented at the SETAC Europe Meeting 2018 in Rome, showing the current state of the process of ringtesting Glyceria maxima. ToxRat performed the statistical evaluation.
Testing the emergent macrophyte, Glyceria maxima, in a water-sediment system
ToxRat was asked to contribute to the Duckweed Forum: How can our software support the statistical evaluation of Lemna Growth Inhibitions tests?
The article describes the features of our ToxRat software and how to use it in ecotoxicology, with Duckweed Test as an example.
ToxRat again contributes to the postgraduate training program "Ecotoxicology": From 11.-15. December 2017 Toni Ratte will educate 18 participants in "Statistics in Ecotoxicology". The trainig program is organized by SETAC GLB (Society of Environmental Toxicology and Chemistry - German Language Branch) and GDCh (Gesellschaft Deutscher Chemiker). Fore more information please click here.
A poster presented at the SETAC North America 38th Annual Meeting, 12-16 November, Minneapolis, USA, shows first results of a ringtest with Glyceria maxima. ToxRat performed the statistical evaluation.
A PROPOSED RING-TEST PROTOCOL FOR THE EMERGENT MACROPHYTE, GLYCERIA MAXIMA, IN A WATER‐SEDIMENT SYSTEM
Another opportunity to meet us (again) was given at the SETAC Europe Conference, hold from 7. to 11. May in Brussels.
Several users took the opportunity to ask their questions to us from face to face.
Both users and interested persons catched up on what is the idea of ToxRat and who is the team behind ToxRat.
January 2002 - January 2017: 15 Years ToxRat
In 2017 we celebrate our 15th Anniversary.
We completed 15 years of software developping, statistical trainings and - especially - providing service and assistance related to statistical evaluation of biotests in ecotoxicology. We are particularly pleased about an increasing number of ToxRat users in Europe and all over the world.
We´d like to thank all business partners and customers for their loyalty and we are looking forward to continue our cooperation in the future.
We performed the statistical evaluation of a study carried out on behalf of the Federal Environment Agency (UBA) - the first publication of the results is now available:
Recommendation for a test battery for the ecotoxicological evaluation of the environmental safety of construction products.
Stefan Gartiser, Ines Heisterkamp, Ute Schoknecht, Nicole Bandow, Michael Burkhardt,Monika Ratte, Outi Ilvonen
We are pleased to find ToxRat recommended as software for statistical evaluation of biotest data in the recent OECD Guideline for the Lymnea stagnalis Reproduction Test (OECD 243).
We see this as confirmation and as an incentive to continue on our path with ToxRat developping.
ToxRat attended the SETAC Europe Conference 2016 from 23.-26. May in Nantes, France, as an exhibitor (booth No 23).
Time for a change:
How do you like our new Flyer ?
In December 2015 ToxRat Solutions again hold a whole week seminar "Statistics in ecotoxicology" as part of the postgraduate training program "Ecotoxicology", organized by SETAC GLB (Society of Environmental Toxicology and Chemistry - German Language Branch) and the GDCh (Gesellschaft Deutscher Chemiker). For more information click here.
The Update ToxRat 3.2 has been released and is available for download as demo or as update in the customer area of our website.
You are a ToxRat user? Then you will be informed and will get your registration keys automatically via email.
Find more information about ToxRat 3.2.0 in the customer area!
New statistical test for analyzing reproduction data - A contribution to the discussion about NOEC determination from reproduction data
R. Lehmann et al: A new approach to overcome shortcomings with multiple testing of reproduction data in ecotoxicology. Journal Stochastic Envirnonmental Research and Risk Assessment:
The Update ToxRat 3 has been released and is available for download as demo or as update in the customer area of our website.
You are a ToxRat user? Then you will be informed and will get your registration keys automatically via email.
Find more information here: What is new in ToxRat 3.pdf
Exhibiton in Barcelona
ToxRat was presented to the 2700 participants of the SETAC Europe 25th Annual Meeting, 3.-7. May 2015, in Barcelona, Spain, at exhibition booth no 18.
ToxRat website for mobile devices
The performance of our website has been extended to mobile devices. We are looking forward to present a responsive website for your smartphone, tablet PC, etc.
Support via online-meeting
In addition to our support by email and phone, you may contact us by online-meetings and presentations. Get your individual meeting-ID on request.
Access to ToxRat Online Support (please contact us for link and meeting ID):
Update ToxRat 3.0.beta is available
In view of the huge amount of new functions and features, a beta test phase of about several months is scheduled.
For more information see here.
Thank you very much...
...to all those who visited us at our booth during the SETAC Europe Annual Meeting 2014, held in Basel, Switzerland, from May 11 to May 15. It was a great pleasure to meet you!
A whole week "Statistics in ecotoxicology" - ToxRat Solutions´ contribution to the postgraduate training program "Ecotoxicology", organized by SETAC GLB (Society of Environmental Toxicology and Chemistry - German Language Branch) and the GDCh (Gesellschaft Deutscher Chemiker). For details click here.
15 participants learned about how to select an appropriate statistical test and how to assess the results.
Publication of the results of an international ring test of the sediment-contakt-test with Myriophyllum aquaticum is in press:
"Inter-laboratory trial of a standardized sediment contact test with the aquatic plant Myriophyllum aquaticum (ISO 16191)", Feiler et al., Environmental Toxicology and Chemistry
Co-Author of a Poster Presentation at the SETAC Europe Conference, Glasgow, Schottland: "A proposed OECD Test guideline for the submerged Macrophyte, Myriophyllum, in a Water-Sediment System."
Results of a Myriophyllum Ringtest under the Auspices of the SETAC Aquatic Macrophyte Ecotoxicology Group (AMEG) (Report available, see below).
ToxRat attended the 23 rd SETAC-Europe Annual Meeting in Glasgow, Scotland, as an exhibitor.
ToxRat Solutions performed the Statistical Evaluation of a Ringtest using Myriophyllum aquaticum and Myriophyllum spicatum grown in a Sediment-Water-System. The ringtest was organized under the Auspices of the SETAC Aquatic Macrophyte Ecotoxicology Group (AMEG). The final report is now available.
ToxRat was an Exhibitor at the 6th SETAC World Congress, Berlin, Germany, May 20-24, 2012
ToxRat Solutions performed the Statistical Evaluation of an International Ring Test according to "Sediment contact test with Myriophyllum aquaticum (ISO/DIS 16191)". Results were presented by Feiler et al. at the SETAC World Congress, Berlin, May 2012:
New focal point for Hans Toni Ratte
ToxRat-Developer Hans Toni Ratte has retired from his post as professor at the Technical University of Aachen at Decemer 1st 2011. In future he will focus on his expertise in statistical evaluation of biotests, especially on programing and developing the ToxRat-Software.
The 16th Annual SETAC GLB Meeting took place from September 18 to 20 at
the University Koblenz-Landau. ToxRat paricipated as exhibitor.
ToxRat´s website has been completey relaunched. Established contents as well as new topics are presented in a new design and with reorganized structure. It aimes to be informative and quite clearly. Simply enjoy!
ToxRat Solutions GmbH performed the Statistical Evaluation of an Inter-Laboratory Ring Test with Myriophyllum spicatum in a water-only-system, organized by the German Federal Environment Agency (UBA). The Final Report is available as pdf.
First results are published as a poster on the SETAC Europe 21th Annual Meeting, Milan, 15.5.-19.5.2011.
Please find the answer to your question immediatly and regardless of date or time in our new area for Frequently Asked Questions, (FAQ). Here both questions about software operation and about general statistics will be answered such as "What´s the difference between Dunnett-Test and William-Test?" "ToxRat indicates an ECx value as being "not valid" - What does this mean?"
ToxRat is exhibitor at the Annual Meeting of the “GDCh Fachgruppe Umweltchemie” and the “SETAC GLB”, 6.-9. September 2010, Dessau-Roßlau, Germany
Attendance in SETAC Europe 20th Annual Meeting, Seville, 23.5. -27.5.10
ToxRat is registered as Community Trade Mark at the OHIM (Office for Harmonization in the Internal market), Alicante, Spain see certificate
Update 2.10.05 released. Find more information here.
ToxRat is exhibitor at the 14th Annual SETAC GLB Meeting in Weihenstephan, Germany (5.10.-7.10.09).
Attendance in SETAC Europe 19th Annual Meeting, Göteborg, 31.5. -3.6.09
Update ToxRat 2.10 available.
Additional statistical methods implemented (Shapiro-Wilks, Levene-Test), further biotests added (OECD 216 (Nitrogen Transformation), 217 (Carbon Transformation), 226 (Hypoaspis), ISO: Ames Fluctuation Test, Arthrobacter...etc..), Dose response calculation enhanced.
Workshop “Introduction to Biostatistics and ToxRat Solutions”, University of Aveiro, Portugal, July 7-11 2008
Attendance in SETAC Europe 18th Annual Meeting, Warsaw, 25.-29. May